ATR

All methods over the ±5 window, side by side.

PSPA

CDDM

MLP-attr

Normalized values from positional scanning peptide array

PSPA measures pT, so at flanking positions the pS row is a duplicate of the pT row. At position 0 the acceptor identity (pS, pT, pY) is genuine.

Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Position-wise Probabilities (±5 window)

Log-Odds (±5 window)

Motifs stratified by phospho-acceptor (S / T / Y)

K-means sub-motif clusters

Signed attribution PSSM distilled from the CDDM discriminative MLP (in-silico saturation mutagenesis). Letters above 0 are enriched, below are depleted; this is not a probability distribution.

MLP-attribution PSSM (±5, signed)

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substrate_uniprot	site	source	substrate_genes	site_seq
O00213	S228	PSP	APBB1 FE65 RIR	LLFGMRNSAASDEDSSWATLsQGSPSYGSPEDTDSFWNPNA
O14757	S296	PSP	CHEK1 CHK1	PRVtsGGVsEsPsGFsKHIQsNLDFsPVNsAssEENVKYss
O14757	S317	GPS6\|SIGNOR\|ELM\|iPTMNet\|PSP	CHEK1 CHK1	NLDFsPVNsAssEENVKYsssQPEPRTGLsLWDtsPsYIDK
O14757	S345	GPS6\|SIGNOR\|ELM\|iPTMNet\|PSP	CHEK1 CHK1	LsLWDtsPsYIDKLVQGISFsQPTCPDHMLLNSQLLGTPGS
O15360	S1449	GPS6\|SIGNOR\|PSP	FANCA FAA FACA FANCH	DPEVSAALQSRQQAAPDADLsQEPHLF______________
O43542	S225	SIGNOR\|PSP	XRCC3	GMARLVVIDSVAAPFRCEFDsQASAPRARHLQSLGATLREL
O43543	S247	PSP	XRCC2	LCKAWQQLVKHRMFFSKQDDsQSSNQFSLVSRCLKSNSLKK
O60934	S343	SIGNOR\|PSP	NBN NBS NBS1 P95	CDPQGHPSTGLKtttPGPsLsQGVsVDEKLMPSAPVNTTTY
O60934	S615	PSP	NBN NBS NBS1 P95	MDIETNDtFsDEAVPEssKIsQENEIGKKRELKEDSLWSAK
O75717	T826	SIGNOR\|PSP	WDHD1 AND1	LILAQKLSELAVEKAAELTAtQVEEEEEEEDFRKKLNAGYs
O75943	S646	GPS6\|SIGNOR\|PSP	RAD17 R24L	EESLGEPtQATVPETWSLPLsQNSASELPAsQPQPFSAQGD
O75943	S656	GPS6\|SIGNOR\|PSP	RAD17 R24L	TVPETWSLPLsQNSASELPAsQPQPFSAQGDMEENIIIEDy
O94880	S294	PSP	PHF14 KIAA0783	KVLsRNsADDEELtNDsLtLsQsKsNEDsLILEKsQNWSSQ
O96017	T68	SIGNOR\|PSP	CHEK2 CDS1 CHK2 RAD53	NSsQSSHSSSGTLSsLETVStQELYsIPEDQEPEDQEPEEP
P04637	S15	SIGNOR\|PSP	TP53 P53	______MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPL
P04637	S20	iPTMNet	TP53 P53	_MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQAM
P04637	S37	iPTMNet\|PSP	TP53 P53	EtFsDLWKLLPENNVLsPLPsQAMDDLMLsPDDIEQWFtED
P04637	T18	iPTMNet	TP53 P53	___MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQ
P06748	S125	PSP	NPM1 NPM	GsGPVHIsGQHLVAVEEDAEsEDEEEEDVKLLsIsGKRsAP
P08047	S101	PSP	SP1 TSFP1	SQGPSQSGGTGELDLTATQLsQGANGWQIISSSSGATPTSK
P09874	S179	SIGNOR\|PSP	PARP1 ADPRT PPOL	HPGCFVKNREELGFRPEYsAsQLKGFsLLAtEDKEALKKQL
P15927	S174	PSP	RPA2 REPA2 RPA32 RPA34	EFTTHILEVINAHMVLSKANsQPSAGRAPISNPGMSEAGNF
P15927	S33	SIGNOR\|PSP	RPA2 REPA2 RPA32 RPA34	sYGGAGGYtQsPGGFGsPAPsQAEKKSRARAQHIVPCTIsQ
P15927	S52	PSP	RPA2 REPA2 RPA32 RPA34	PsQAEKKSRARAQHIVPCTIsQLLSATLVDEVFRIGNVEIs
P15927	S72	PSP	RPA2 REPA2 RPA32 RPA34	sQLLSATLVDEVFRIGNVEIsQVTIVGIIRHAEKAPTNIVY
P15927	T21	PSP	RPA2 REPA2 RPA32 RPA34	MWNsGFEsYGsssYGGAGGYtQsPGGFGsPAPsQAEKKSRA
P16104	S140	GPS6	H2AX H2AFX	KtsAtVGPKAPSGGKKAtQAsQEy_________________
P16220	S107	SIGNOR\|PSP	CREB1	QISTIAEsEDsQEsVDsVTDsQKRREILsRRPsYRKILNDL
P23025	S173	SIGNOR\|iPTMNet\|PSP	XPA XPAC	CDLEKREPPLKFIVKKNPHHsQWGDMKLYLKLQIVKRSLEV
P23025	S196	SIGNOR\|iPTMNet\|PSP	XPA XPAC	GDMKLYLKLQIVKRSLEVWGsQEALEEAKEVRQENREKMKQ
P23508	S118	SIGNOR\|PSP	MCC	RLQGTTIREEDEySELRsELsQsQHEVNEDSRSMDQDQTSV
P23508	S120	SIGNOR\|PSP	MCC	QGTTIREEDEySELRsELsQsQHEVNEDSRSMDQDQTSVSI
P25205	S535	PSP	MCM3	GDAMPLGSAVDILATDDPNFsQEDQQDTQIYEKHDNLLHGT
P27707	S74	PSP	DCK	PVARWCNVQstQDEFEELtMsQKNGGNVLQMMYEKPERWSF
P35568	S270	PSP	IRS1	HETILEAMRAMSDEFRPRsKsQsssNCSNPISVPLRRHHLN
P38398	S1143	GPS6\|SIGNOR\|PSP	BRCA1 RNF53	DFSPYLISDNLEQPMGSSHAsQVCSETPDDLLDDGEIKEDt
P38398	S1280	GPS6\|SIGNOR\|PSP	BRCA1 RNF53	LLSLKNsLNDCsNQVILAKAsQEHHLsEETKCSASLFSSQC
P38398	S1387	GPS6\|SIGNOR	BRCA1 RNF53	EAASGCESETSVSEDCSGLSsQSDILTtQQRDTMQHNLIKL
P38398	S1423	GPS6\|SIGNOR\|ELM\|iPTMNet\|PSP	BRCA1 RNF53	NLIKLQQEMAELEAVLEQHGsQPSNSYPSIISDSSALEDLR
P38398	S1457	GPS6\|SIGNOR\|ELM\|iPTMNet\|PSP	BRCA1 RNF53	SALEDLRNPEQSTSEKAVLtsQKssEYPIsQNPEGLsADKF
P38398	S1524	GPS6\|ELM\|iPTMNet\|PSP	BRCA1 RNF53	LDDRWYMHSCsGSLQNRNyPsQEELIKVVDVEEQQLEEsGP
P38398	T1394	GPS6\|SIGNOR	BRCA1 RNF53	SETSVSEDCSGLSsQSDILTtQQRDTMQHNLIKLQQEMAEL
P39880	S1357	PSP	CUX1 CUTL1	sCDGVEATEGPGsADTEEPKsQGEAEREEVPRPAEQTEPPP
P42771	S140	PSP	CDKN2A CDKN2 MTS1	ELGHRDVARYLRAAAGGTRGsNHARIDAAEGPsDIPD____
P42771	S152	PSP	CDKN2A CDKN2 MTS1	AAAGGTRGsNHARIDAAEGPsDIPD________________
P42771	S7	PSP	CDKN2A CDKN2 MTS1	______________MEPAAGssMEPSADWLATAAARGRVEE
P42771	S8	PSP	CDKN2A CDKN2 MTS1	_____________MEPAAGssMEPSADWLATAAARGRVEEV
P49006	S71	PSP	MARCKSL1 MLP MRP	VNGtDEAAGATGDAIEPAPPsQGAEAKGEVPPKEtPKKKKK
P49591	S101	PSP	SARS1 SARS SERS	PENVLSFDDLTADALANLKVsQIKKVRLLIDEAILKCDAER
P49591	S241	PSP	SARS1 SARS SERS	IPIYTPFFMRKEVMQEVAQLsQFDEELyKVIGKGSEKSDDN
P49736	S108	GPS6\|SIGNOR\|PSP	MCM2 BM28 CCNL1 CDCL1 KIAA0030	DAYEAEGLALDDEDVEELtAsQREAAERAMRQRDREAGRGL
P54132	T122	PSP	BLM RECQ2 RECQL3	GGSKSLLPDFLQtPKEVVCTtQNtPtVKKSRDTALKKLEFs
P54132	T99	PSP	BLM RECQ2 RECQL3	NTTNQQRVKDFFKNAPAGQEtQRGGSKSLLPDFLQtPKEVV
P55072	S784	PSP	VCP HEL-220 HEL-S-70	QsRGFGsFRFPsGNQGGAGPsQGsGGGtGGsVYTEDNDDDL
P78527	S2612	PSP	PRKDC HYRC HYRC1	DSDWRFRSTVLtPMFVEtQAsQGtLQtRtQEGsLSARWPVA
P78527	T2609	SIGNOR\|PSP	PRKDC HYRC HYRC1	YTIDSDWRFRSTVLtPMFVEtQAsQGtLQtRtQEGsLSARW
P78527	T2647	PSP	PRKDC HYRC HYRC1	ARWPVAGQIRAtQQQHDFtLtQtADGRssFDWLTGsstDPL
Q00987	S407	GPS6\|SIGNOR\|ELM\|iPTMNet\|PSP	MDM2	QSQESEDysQPSTSsSIIySsQEDVKEFEREEtQDKEEsVE
Q01094	S31	GPS6\|SIGNOR\|ELM\|iPTMNet\|PSP	E2F1 RBBP3	PCAPALEALLGAGALRLLDSsQIVIISAAQDASAPPAPTGP
Q01844	T79	PSP	EWSR1 EWS	ATYGQTAYATSYGQPPTGYttPtAPQAYSQPVQGYGTGAYD
Q02952	S732	PSP	AKAP12 AKAP250	QKADEAGKDKEtGtDGILAGsQEHDPGQGsssPEQAGsPTE
Q03164	S516	SIGNOR\|PSP	KMT2A ALL1 CXXC7 HRX HTRX MLL MLL1 TRX1	IQVLPEERsDtPEVHPPLPIsQsPENEsNDRRSRRYsVSER
Q12888	S166	PSP	TP53BP1	KEEDTSGNTTHSLGAEDTASsQLGFGVLELsQsQDVEENTV
Q12888	S176	PSP	TP53BP1	HSLGAEDTASsQLGFGVLELsQsQDVEENTVPYEVDKEQLQ
Q12888	S178	PSP	TP53BP1	LGAEDTASsQLGFGVLELsQsQDVEENTVPYEVDKEQLQsV
Q12888	S452	PSP	TP53BP1	ASTPISQSTPVFPPGSLPIPsQPQFSHDIFIPSPSLEEQSN
Q12888	S831	PSP	TP53BP1	EYEGDLKsGtAEtEPVEQDssQPsLPLVRADDPLRLDQELQ
Q12888	T302	PSP	TP53BP1	QELMEsGLQIQKsPEPEVLstQEDLFDQsNKtVssDGCstP
Q13098	S474	PSP	GPS1 COPS1 CSN1	MLRAAVLRNQIHVKsPPREGsQGELtPANsQsRMstNM___
Q13263	S824	GPS6	TRIM28 KAP1 RNF96 TIF1B	KFSAVLVEPPPMsLPGAGLssQELsGGPGDGP_________
Q13315	S1981	SIGNOR\|PSP	ATM	YADKKSMDDQEKRSLAFEEGsQSTtIssLSEKsKEETGISL
Q13535	T1989	PSP	ATR FRP1	VHQALIVLQKGVELCFPENEtPPEGKNMLIHGRAMLLVGRF
Q14191	S1141	SIGNOR\|PSP	WRN RECQ3 RECQL2	GSNISKKsIMVQsPEKAySSsQPVISAQEQETQIVLYGKLV
Q14676	S513	PSP	MDC1 KIAA0170 NFBD1	GDsDDsVEADKssPGIHLERsQAsttVDINtQVEKEVPPGS
Q14683	S957	PSP	SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1	DIKLPLSKGtMDDIsQEEGssQGEDsVsGsQRIssIYAREA
Q14683	S966	GPS6\|PSP	SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1	tMDDIsQEEGssQGEDsVsGsQRIssIYAREALIEIDYGDL
Q6PCD5	S46	GPS6	RFWD3 RNF201	MASSQGGPALLQPVPADVVSsQGVPSILQPAPAEVISsQAT
Q6PCD5	S63	GPS6	RFWD3 RNF201	VVSsQGVPSILQPAPAEVISsQATPPLLQPAPQLSVDLTEV
Q6PGQ7	T501	PSP	BORA C13orf34	AESSVIPCESSNIQMDsGYNtQNCGSNIMDTVGAESYCKES
Q7Z6Z7	S2391	PSP	HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272	RsGEDEsQEDVLMDEAPsNLsQAsTLQANREDSMNILDPED
Q8IUH4	S8	SIGNOR\|PSP	ZDHHC13 HIP14L HIP3RP	_____________MEGPGLGsQCRNHSHGPHPPGFGRYGIC
Q8IUQ4	S19	GPS6\|SIGNOR\|PSP	SIAH1 HUMSIAH	__MSRQTATALPTGTSKCPPsQRVPALTGTTASNNDLASLF
Q8IX01	T7	PSP	SUGP2 KIAA0365 SFRS14	______________MAARRItQETFDAVLQEKAKRYHMDAS
Q8IYD8	S1045	PSP	FANCM KIAA1596	CAEHLRSDKCTCLLSHSAVNsQQNLELNSLKCINYPSEKSC
Q8IZL8	S1033	PSP	PELP1 HMX3 MNAR	GtEEERGADTAPTLAPEALPsQGEVEREGEsPAAGPPPQEL
Q8N163	T454	SIGNOR\|PSP	CCAR2 DBC1 KIAA1967	PTLEEWEALCQQKAAEAAPPtQEAQGEtEPTEQAPDALEQA
Q8N4S0	S154	PSP	CCDC82 HT025	DNDLNKQTGQIIEDDQEKHLsQEDNDLNKQTGQIIEDDLEE
Q8NEM0	S322	PSP	MCPH1	LQRNIAGKVVTPDQKQAAGMsQETFEEKYRLsPtLsstKGH
Q8TAQ2	S969	PSP	SMARCC2 BAF170	QHFQQMHQQQQQPPPALPPGsQPIPPTGAAGPPAVHGLAVA
Q8WVB6	S74	PSP	CHTF18 C16orf41 CTF18	EALARGDAAssPAPAAsVGssQGGARKRQVDADLQPAGsLP
Q8WXE1	S68	GPS6\|SIGNOR\|ELM\|iPTMNet\|PSP	ATRIP AGS1	PFGAHGDFtADDLEELDtLAsQALsQCPAAARDVSSDHKVH
Q8WXE1	S72	GPS6\|SIGNOR\|ELM\|iPTMNet\|PSP	ATRIP AGS1	HGDFtADDLEELDtLAsQALsQCPAAARDVSSDHKVHRLLD
Q92831	S264	PSP	KAT2B PCAF	IVELAKMFLNRINYWHLEAPsQRRLRSPNDDISGYKENYTR
Q96RL1	S205	PSP	UIMC1 RAP80 RXRIP110	HTEKTEEEPVsGssGsWDQssQPVFENVNVKSFDRCTGHSA
Q96RU2	S67	SIGNOR\|PSP	USP28 KIAA1515	SNGDITQAVSLLTDERVKEPsQDtVATEPSEVEGSAANKEV
Q96RU2	S714	SIGNOR\|PSP	USP28 KIAA1515	EWEEEQSCKIPQMEsstNsssQDYSTsQEPSVASSHGVRCL
Q96SB4	S408	GPS6\|PSP	SRPK1	VQNLNQESSFLSSQNGDSSTsQETDSCTPITSEVSDTMVCQ
Q96SB4	T326	GPS6\|PSP	SRPK1	QEEsEsPVERPLKENPPNKMtQEKLEEsstIGQDQtLMERD
Q96SD1	S516	GPS6\|PSP	DCLRE1C ARTEMIS ASCID SCIDA SNM1C	NDEITDEsLENFPSSTVAGGsQsPKLFSDsDGESTHISsQN
Q96SD1	S645	GPS6\|PSP	DCLRE1C ARTEMIS ASCID SCIDA SNM1C	SSETHIPEEKSLLNLSTNADsQsssDFEVPstPEAELPKRE
Q99708	T859	SIGNOR\|PSP	RBBP8 CTIP	RFRYIPPNtPENFWEVGFPStQTCMERGYIKEDLDPCPRPK
Q99728	T714	GPS6	BARD1	LVTAGGGQILSRKPKPDSDVtQTINTVAYHARPDSDQRFCt
Q99728	T734	GPS6	BARD1	tQTINTVAYHARPDSDQRFCtQYIIYEDLCNYHPERVRQGK
Q9BUG6	T422	PSP	ZSCAN5A ZNF495 ZSCAN5	HQRTHTGERPYTCDVCQKQFtQKSYLKCHKRSHTGEKPFEC
Q9BW19	S26	SIGNOR\|PSP	KIFC1 HSET KNSL2	sPLLEVKGNIELKRPLIKAPsQLPLsGsRLKRRPDQMEDGL
Q9BXW9	S717	SIGNOR\|PSP	FANCD2 FACD	INLLPLLFsQDFAKDGGPVTsQESGQKLVSPLCLAPYFRLL
Q9BXW9	T596	PSP	FANCD2 FACD	IGAVTMAGIMAADRsEsPsLtQERANLSDEQCtQVTSLLQL
Q9BXW9	T608	PSP	FANCD2 FACD	DRsEsPsLtQERANLSDEQCtQVTSLLQLVHSCSEQSPQAS
Q9BXW9	T691	SIGNOR\|PSP	FANCD2 FACD	VPEGDFPFPVKALYGLEEyDtQDGIAINLLPLLFsQDFAKD
Q9H6E5	S750	PSP	TUT1 RBM21	PSHAALAERGPKGHEAAQEWsQGEAGKGASLPSSASWRCAL
Q9NRC8	S134	PSP	SIRT7 SIR2L7	ASIPDYRGPNGVWTLLQKGRsVsAADLSEAEPTLTHMSItR
Q9NRC8	S136	PSP	SIRT7 SIR2L7	IPDYRGPNGVWTLLQKGRsVsAADLSEAEPTLTHMSItRLH
Q9NVI1	S556	PSP	FANCI KIAA1794	AVAGFLLLLKNFKVLGSLSSsQCsQSLSVsQVHVDVHSHYN
Q9NVI1	S559	PSP	FANCI KIAA1794	GFLLLLKNFKVLGSLSSsQCsQSLSVsQVHVDVHSHYNSVA
Q9NVI1	S565	PSP	FANCI KIAA1794	KNFKVLGSLSSsQCsQSLSVsQVHVDVHSHYNSVANETFCL
Q9NZC9	S652	SIGNOR\|PSP	SMARCAL1 HARP	ELKLLLEEAVMLRRLKSDVLsQLPAKQRKIVVIAPGRINAR
Q9NZN8	S101	PSP	CNOT2 CDC36 NOT2 HSPC131 MSTP046	ALGLPMRGMSNNtPQLNRsLsQGtQLPsHVtPTTGVPtMsL
Q9UBU7	S502	SIGNOR\|PSP	DBF4 ASK DBF4A ZDBF1	YKCNIQASVHVSDFSTDNSGsQPKQKsDtVLFPAKDLKEKD
Q9UBU7	S539	SIGNOR\|PSP	DBF4 ASK DBF4A ZDBF1	KEKDLHSIFTHDSGLITINSsQEHLTVQAKAPFHtPPEEPN
Q9UBU7	T449	SIGNOR\|PSP	DBF4 ASK DBF4A ZDBF1	KMSNKCSMLSTAEDDIRQNFtQLPLHKNKQECILDISEHTL
Q9UER7	S424	PSP	DAXX BING2 DAP6	HsADtPEAsLDsGEGPsGMAsQGCPsAsRAETDDEDDEESD
Q9UH99	S12	PSP	SUN2 FRIGG KIAA0668 RAB5IP UNC84B	_________MSRRSQRLtRysQGDDDGssssGGSSVAGsQs
Q9UPV0	S186	GPS6\|PSP	CEP164 KIAA1052 NPHP15	SVSLGSSVESGRQLGELMLPsQGLKTSAYTKGLLGSIyEDK
Q9UQ84	S714	GPS6	EXO1 EXOI HEX1	QCssKDsDSEESDCNIKLLDsQSDQTSKLRLSHFSKKDTPL
Q9Y248	S182	PSP	GINS2 PSF2 CGI-122 DC5 HSPC037	QALNHMYKLRTNLQPLEstQsQDF_________________
Q9Y253	S601	SIGNOR\|PSP	POLH RAD30 RAD30A XPV	VSKLEEsSKATPAEMDLAHNsQSMHASSASKSVLEVtQKAT
Q9Y285	S301	PSP	FARSA FARS FARSL FARSLA	DPAEALQLPMDYVQRVKRtHsQGGYGSQGYKYNWKLDEARK
Q9Y4P3	T433	GPS6	TBL2 WBSCR13 UNQ563/PRO1125	QGHLKRASNESTRQRLQQQLtQAQETLKSLGALKK______