BRSK1

All methods over the ±5 window, side by side.

PSPA

CDDM

MLP-attr

Normalized values from positional scanning peptide array

PSPA measures pT, so at flanking positions the pS row is a duplicate of the pT row. At position 0 the acceptor identity (pS, pT, pY) is genuine.

Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Position-wise Probabilities (±5 window)

Log-Odds (±5 window)

Motifs stratified by phospho-acceptor (S / T / Y)

K-means sub-motif clusters

Signed attribution PSSM distilled from the CDDM discriminative MLP (in-silico saturation mutagenesis). Letters above 0 are enriched, below are depleted; this is not a probability distribution.

MLP-attribution PSSM (±5, signed)

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substrate_uniprot	site	source	substrate_genes	site_seq
A6NKT7	S980	Sugiyama	RGPD3 RGP3	GVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSGAG
O14639	S452	Sugiyama	ABLIM1 ABLIM KIAA0059 LIMAB1	PtPsAEGyQDVRDRMIHRstsQGsINsPVySRHsYtPTTSR
O14715	S979	Sugiyama	RGPD8 RANBP2ALPHA RANBP2L1 RANBP2L3	GVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSGAG
O43423	S100	Sugiyama	ANP32CP PP32R1	AEKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCE
O43707	T445	Sugiyama	ACTN4	HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O60841	S186	Sugiyama	EIF5B IF2 KIAA0741	EDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKN
O60841	S190	Sugiyama	EIF5B IF2 KIAA0741	NsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGP
O95155	S105	Sugiyama	UBE4B HDNB1 KIAA0684 UFD2	LsssPsNsLEtQsQsLsRsQsMDIDGVSCEKsMsQVDVDsG
O95218	S181	Sugiyama	ZRANB2 ZIS ZNF265	DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR
O95626	S104	Sugiyama	ANP32D PP32R2	AEKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCE
P04075	S36	Sugiyama	ALDOA ALDA	LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04406	S241	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406	T237	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04792	S82	Sugiyama	HSPB1 HSP27 HSP28	AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05386	S104	Sugiyama	RPLP1 RRP1	tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387	S105	Sugiyama	RPLP2 D11S2243E RPP2	GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P07195	T323	Sugiyama	LDHB	sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07737	S28	Sugiyama	PFN1	IDNLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEV
P07737	S30	Sugiyama	PFN1	NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV
P07900	S52	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs
P09132	S69	Sugiyama	SRP19	IQDVCSAVGLNVFLEKNKMYsREWNRDVQYRGRVRVQLKQE
P0DJD0	S964	Sugiyama	RGPD1 RANBP2L6 RGP1	GVIFGQTSSTFTFADVAKstsGEGFQFGKKDPNFKGFSGAG
P0DPH7	S48	Sugiyama	TUBA3C TUBA2	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P10636	S579	GPS6\|EPSD	MAPT MAPTL MTBT1 TAU	RLQTAPVPMPDLKNVKsKIGstENLKHQPGGGKVQIINKKL
P10809	T428	Sugiyama	HSPD1 HSP60	GtsDVEVNEKKDRVtDALNAtRAAVEEGIVLGGGCALLRCI
P12004	S172	Sugiyama	PCNA	sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE
P13797	S540	Sugiyama	PLS3	NDDIIVNWVNRTLSEAGKSTsIQSFKDKTISSSLAVVDLID
P13798	S185	Sugiyama	APEH D3F15S2 D3S48E DNF15S2	VAEKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQ
P14625	T171	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P16949	S46	Sugiyama	STMN1 C1orf215 LAP18 OP18	PRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAEERRKsHEA
P20810	S45	SIGNOR	CAST	KHKKQAVKTEPEKKSQsTKLsVVHEKKSQEGKPKEHTEPKS
P23258	S131	SIGNOR\|EPSD\|PSP	TUBG1 TUBG	GEKIHEDIFDIIDREADGSDsLEGFVLCHSIAGGTGSGLGS
P23258	S385	EPSD\|PSP	TUBG1 TUBG	PYLPSAHRVSGLMMANHTSIsSLFERTCRQYDKLRKREAFL
P26373	S77	Sugiyama	RPL13 BBC1 OK/SW-cl.46	PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P30291	S642	GPS6\|SIGNOR\|iPTMNet\|EPSD\|PSP	WEE1	STTQSNRTSRLIGKKMNRSVsLTIY________________
P30305	S375	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CDC25B CDC25HU2	tPPEEQQEAEEPKARVLRsKsLCHDEIENLLDSDHRELIGD
P30307	S216	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CDC25C	EFsLKDQEAKVSRsGLYRsPsMPENLNRPRLKQVEKFKDNt
P39687	S104	Sugiyama	ANP32A C15orf1 LANP MAPM PHAP1	AEKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCE
P40818	S719	Sugiyama	USP8 KIAA0055 UBPY	KPQIPAERDREPSKLKRsyssPDItQAIQEEEKRKPTVtPT
P43487	S60	Sugiyama	RANBP1	TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P49792	S1955	Sugiyama	RANBP2 NUP358	GVIFGQTSSTFTFADLAKstsGEGFQFGKKDPNFKGFSGAG
P49840	Y279	Sugiyama	GSK3A	LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49841	Y216	Sugiyama	GSK3B	LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P54105	S198	Sugiyama	CLNS1A CLCI ICLN	TAEGQATLERLEGMLsQsVssQYNMAGVRtEDsIRDyEDGM
P68363	S439	Sugiyama	TUBA1B	SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
P68363	S48	Sugiyama	TUBA1B	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q07021	S210	Sugiyama	C1QBP GC1QBP HABP1 SF2P32	EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS
Q08AD1	S1313	Sugiyama	CAMSAP2 CAMSAP1L1 KIAA1078	sLNtGDNEsVHsGKRtPRsEsVEGFLsPsRCGsRNGEKDWE
Q08AD1	S464	Sugiyama	CAMSAP2 CAMSAP1L1 KIAA1078	FDKEDSVQRstPNRGITRsIsNEGLtLNNsHVsKHIRKNLS
Q13131	T183	EPSD\|PSP	PRKAA1 AMPK1	NAKIADFGLsNMMsDGEFLRtsCGsPNyAAPEVISGRLYAG
Q13464	S576	Sugiyama	ROCK1	TESDTAVRLRKSHTEMSKSIsQLESLNRELQERNRILENSK
Q14568	S52	Sugiyama	HSP90AA2P HSP90AA2 HSPC2 HSPCAL3	LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS
Q15293	S80	Sugiyama	RCN1 RCN	HEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGDGFVt
Q5H9R7	S579	Sugiyama	PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3	IDQFGFNDEKFADQDDIGNVsFDRVSDINFTLNTNESGNIA
Q6GYQ0	T798	Sugiyama	RALGAPA1 GARNL1 KIAA0884 TULIP1	tGNEVFGALNEEQPLPRssstsDILEPFTVERAKVNKEDMS
Q6PEY2	S48	Sugiyama	TUBA3E	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36	S439	Sugiyama	TUBA1A TUBA3	SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
Q71U36	S48	Sugiyama	TUBA1A TUBA3	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q7Z3J3	S980	Sugiyama	RGPD4 RGP4	GVIFGQTSSTFTFADVAKstsGEGFQFGKKDPNFKGFSGAG
Q7Z460	S545	Sugiyama	CLASP1 KIAA0622 MAST1	yHTLESSyQKALQSHLKNSDsIVsLPQsDRsssssQEsLNR
Q8WWI1	T932	Sugiyama	LMO7 FBX20 FBXO20 KIAA0858	VtPRPFGsQtRGISsLPRsYtMDDAWKYNGDVEDIKRtPNN
Q93045	S80	Sugiyama	STMN2 SCG10 SCGN10	PPsPISEAPRTLAsPKKKDLsLEEIQKKLEAAEERRKsQEA
Q96HE7	S143	Sugiyama	ERO1A ERO1L UNQ434/PRO865	EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD
Q96L92	S51	Sugiyama	SNX27 KIAA0488 My014	AGNGGGGGGGPRVVRIVKsEsGYGFNVRGQVsEGGQLRSIN
Q99666	S979	Sugiyama	RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6	GVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSGAG
Q9BQE3	S48	Sugiyama	TUBA1C TUBA6	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9NVR5	S773	Sugiyama	DNAAF2 C14orf104 KTU	EFIKEKSATCSNEEKDNLNEsVITEEKETDGDHLsSLLNKT
Q9P1Y5	S431	Sugiyama	CAMSAP3 KIAA1543	FGLDSDVDVVMGDPVLLRsVssDsLGPPRPAPARTPtQPPP