BRSK2

All methods over the ±5 window, side by side.
PSPA
CDDM
MLP-attr
Normalized values from positional scanning peptide array
PSPA measures pT, so at flanking positions the pS row is a duplicate of the pT row. At position 0 the acceptor identity (pS, pT, pY) is genuine.
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Position-wise Probabilities (±5 window)
Log-Odds (±5 window)
Motifs stratified by phospho-acceptor (S / T / Y)
K-means sub-motif clusters
Signed attribution PSSM distilled from the CDDM discriminative MLP (in-silico saturation mutagenesis). Letters above 0 are enriched, below are depleted; this is not a probability distribution.
MLP-attribution PSSM (±5, signed)
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substrate_uniprot site source substrate_genes site_seq
A6NKT7 S978 Sugiyama RGPD3 RGP3 GRGVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSG
A6NKT7 S980 Sugiyama RGPD3 RGP3 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSGAG
O00273 S37 Sugiyama DFFA DFF1 DFF45 H13 TLKPCLLRRNysREQHGVAAsCLEDLRSKACDILAIDKSLT
O14639 S452 Sugiyama ABLIM1 ABLIM KIAA0059 LIMAB1 PtPsAEGyQDVRDRMIHRstsQGsINsPVySRHsYtPTTSR
O14715 S977 Sugiyama RGPD8 RANBP2ALPHA RANBP2L1 RANBP2L3 GRGVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSG
O14715 S979 Sugiyama RGPD8 RANBP2ALPHA RANBP2L1 RANBP2L3 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSGAG
O14974 S445 Sugiyama PPP1R12A MBS MYPT1 EEERKDEsPATWRLGLRKtGsyGALAEItASKEGQKEKDTA
O43815 S229 Sugiyama STRN TEAEVKETAMIAKSELtDsAsVLDNFKFLEsAAADFsDEDE
O43852 S69 Sugiyama CALU HDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKDGFVt
O94885 T460 Sugiyama SASH1 KIAA0790 PEPE1 IKsPtASRISLGKKVKSVKEtMRKRMSKKYSSSVSEQDsGL
O95155 S105 Sugiyama UBE4B HDNB1 KIAA0684 UFD2 LsssPsNsLEtQsQsLsRsQsMDIDGVSCEKsMsQVDVDsG
O95218 S181 Sugiyama ZRANB2 ZIS ZNF265 DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95714 S2928 Sugiyama HERC2 ILLGRIRAEEEDLAAVPFLAsDNEEEEDEKGNSGsLIRKKA
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05423 S250 Sugiyama POLR3D BN51 BN51T AKMKAPPKAARKTPGLPKDVsVAELLRELSLTKEEELLFLQ
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07737 S30 Sugiyama PFN1 NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV
P07900 S399 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK
P07900 S52 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs
P08238 S391 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P0CG47 S57 Sugiyama UBB PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM
P0CG48 S57 Sugiyama UBC PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM
P0DJD0 S962 Sugiyama RGPD1 RANBP2L6 RGP1 GRGVIFGQTSSTFTFADVAKstsGEGFQFGKKDPNFKGFSG
P0DJD0 S964 Sugiyama RGPD1 RANBP2L6 RGP1 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDPNFKGFSGAG
P10636 S579 GPS6|EPSD MAPT MAPTL MTBT1 TAU RLQTAPVPMPDLKNVKsKIGstENLKHQPGGGKVQIINKKL
P11279 S141 Sugiyama LAMP1 NLSDTHLFPNASSKEIKtVEsITDIRADIDKKYRCVSGTQV
P12004 S172 Sugiyama PCNA sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P15531 S120 Sugiyama NME1 NDPKA NM23 KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P15531 S122 Sugiyama NME1 NDPKA NM23 GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P16949 S46 Sugiyama STMN1 C1orf215 LAP18 OP18 PRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAEERRKsHEA
P18615 S115 Sugiyama NELFE RD RDBP KLKDPEKGPVPTFQPFQRsIsADDDLQEsSRRPQRKsLyEs
P18615 S51 Sugiyama NELFE RD RDBP ALKKQSSSSTTSQGGVKRsLsEQPVMDTATATEQAKQLVKS
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P22059 S240 Sugiyama OSBP OSBP1 DLSTCNDLIAKHGTALQRsLsELEsLKLPAESNEKIKQVNE
P22626 S189 Sugiyama HNRNPA2B1 HNRPA2B1 IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P27797 S53 Sugiyama CALR CRTC WtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDAR
P30291 S642 GPS6|iPTMNet|EPSD WEE1 STTQSNRTSRLIGKKMNRSVsLTIY________________
P30307 S216 iPTMNet CDC25C EFsLKDQEAKVSRsGLYRsPsMPENLNRPRLKQVEKFKDNt
P30622 S195 Sugiyama CLIP1 CYLN1 RSN AAKEPsAtPPISNLTKtAsEsIsNLsEAGsIKKGERELKIG
P31943 S23 Sugiyama HNRNPH1 HNRPH HNRPH1 LGTEGGEGFVVKVRGLPWsCsADEVQRFFSDCKIQNGAQGI
P35221 S641 Sugiyama CTNNA1 GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P40818 S719 Sugiyama USP8 KIAA0055 UBPY KPQIPAERDREPSKLKRsyssPDItQAIQEEEKRKPTVtPT
P43490 S472 Sugiyama NAMPT PBEF PBEF1 EYGQDLLHTVFKNGKVTKsysFDEIRKNAQLNIELEAAHH_
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P49327 T2215 Sugiyama FASN FAS DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN
P49792 S1953 Sugiyama RANBP2 NUP358 GRGVIFGQTSSTFTFADLAKstsGEGFQFGKKDPNFKGFSG
P49792 S1955 Sugiyama RANBP2 NUP358 GVIFGQTSSTFTFADLAKstsGEGFQFGKKDPNFKGFSGAG
P49815 S1387 EPSD|PSP TSC2 TSC4 GGRPsVDLsFQPsQPLsKssssPELQtLQDILGDPGDKADV
P52565 S174 PSP ARHGDIA GDIA1 EEyEFLtPVEEAPKGMLARGsYsIKSRFTDDDKTDHLSWEW
P52594 S293 Sugiyama AGFG1 HRB RAB RIP GSAASVNANFAHFDNFPKsssADFGtFNTsQSHQTASAVSK
P55010 S10 Sugiyama EIF5 ___________MSVNVNRsVsDQFyRyKMPRLIAKVEGKGN
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62979 S57 Sugiyama RPS27A UBA80 UBCEP1 PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGA
P62987 S57 Sugiyama UBA52 UBCEP2 PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGI
P63220 S65 Sugiyama RPS21 RFNGQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF__
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 S86 Sugiyama RPL24 EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731 T83 Sugiyama RPL24 QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA
Q00536 S12 EPSD|PSP CDK16 PCTAIRE1 PCTK1 _________MDRMKKIKRQLsMTLRGGRGIDKTNGAPEQIG
Q00587 S192 Sugiyama CDC42EP1 BORG5 CEP1 MSE55 PHDRDRDGsFPsEPGLRRsDsLLsFRLDLDLGPSLLSELLG
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q08AD1 S1313 Sugiyama CAMSAP2 CAMSAP1L1 KIAA1078 sLNtGDNEsVHsGKRtPRsEsVEGFLsPsRCGsRNGEKDWE
Q08AD1 S464 Sugiyama CAMSAP2 CAMSAP1L1 KIAA1078 FDKEDSVQRstPNRGITRsIsNEGLtLNNsHVsKHIRKNLS
Q13131 T183 SIGNOR|EPSD|PSP PRKAA1 AMPK1 NAKIADFGLsNMMsDGEFLRtsCGsPNyAAPEVISGRLYAG
Q13464 S576 Sugiyama ROCK1 TESDTAVRLRKSHTEMSKSIsQLESLNRELQERNRILENSK
Q13615 S613 Sugiyama MTMR3 KIAA0371 ZFYVE10 YPAPGTSPDDPPLSRLPKtRsyDNLttACDNTVPLASRRCs
Q14568 S52 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15293 S80 Sugiyama RCN1 RCN HEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGDGFVt
Q15751 S1512 Sugiyama HERC1 LtAESRLVHtsPNYRLIKsRsEsDLsQPEsDEEGYALsGRR
Q16531 T1125 Sugiyama DDB1 XAP1 MQEVVANLQYDDGSGMKREAtADDLIKVVEELtRIH_____
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q6GYQ0 T798 Sugiyama RALGAPA1 GARNL1 KIAA0884 TULIP1 tGNEVFGALNEEQPLPRssstsDILEPFTVERAKVNKEDMS
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z3J3 S978 Sugiyama RGPD4 RGP4 GRGVIFGQTSSTFTFADVAKstsGEGFQFGKKDPNFKGFSG
Q7Z3J3 S980 Sugiyama RGPD4 RGP4 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDPNFKGFSGAG
Q7Z417 S652 Sugiyama NUFIP2 KIAA1321 PIG1 NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86VQ1 S223 Sugiyama GLCCI1 QTPsCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQR
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8IWQ3 S367 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 QEDEDLPPRNEIDPPRKRVDsPMLNRHGKRRPERKsMEVLS
Q8IWQ3 S382 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 RKRVDsPMLNRHGKRRPERKsMEVLSVtDGGsPVPARRAIE
Q8IWQ3 S393 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 HGKRRPERKsMEVLSVtDGGsPVPARRAIEMAQHGQRsRsI
Q8IWQ3 S410 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 DGGsPVPARRAIEMAQHGQRsRsIsGASSGLStsPLssPRV
Q8IWQ3 S423 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 MAQHGQRsRsIsGASSGLStsPLssPRVtPHPsPRGsPLPt
Q8IWQ3 S426 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 HGQRsRsIsGASSGLStsPLssPRVtPHPsPRGsPLPtPKG
Q8IWQ3 S427 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 GQRsRsIsGASSGLStsPLssPRVtPHPsPRGsPLPtPKGT
Q8IWQ3 S513 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 HRRKLQVPtPEEMSNLtPEssPELAKKSWFGNFISLEKEEQ
Q8IWQ3 T389 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 MLNRHGKRRPERKsMEVLSVtDGGsPVPARRAIEMAQHGQR
Q8IWQ3 T501 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 SIKNSFLGsPRFHRRKLQVPtPEEMSNLtPEssPELAKKSW
Q8IWQ3 T509 Sugiyama BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12 sPRFHRRKLQVPtPEEMSNLtPEssPELAKKSWFGNFISLE
Q8WUF5 S102 Sugiyama PPP1R13L IASPP NKIP1 PPP1R13BL RAI RGsPRKAATDGADtPFGRsEsAPtLHPysPLsPKGRPssPR
Q8WWI1 S706 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 RLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEMQK
Q8WWI1 T932 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 VtPRPFGsQtRGISsLPRsYtMDDAWKYNGDVEDIKRtPNN
Q93045 S80 Sugiyama STMN2 SCG10 SCGN10 PPsPISEAPRTLAsPKKKDLsLEEIQKKLEAAEERRKsQEA
Q96JJ7 S268 Sugiyama TMX3 KIAA1830 TXNDC10 LVALAVIDEKNTSVEHTRLKsIIQEVARDYRDLFHRDFQFG
Q96L92 S51 Sugiyama SNX27 KIAA0488 My014 AGNGGGGGGGPRVVRIVKsEsGYGFNVRGQVsEGGQLRSIN
Q99666 S977 Sugiyama RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6 GRGVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSG
Q99666 S979 Sugiyama RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6 GVIFGQTSSTFTFADVAKstsGEGFQFGKKDLNFKGFSGAG
Q9BX95 S112 Sugiyama SGPP1 SPP1 GLAAELGPAsPRRAGALRRNsLtGEEGQLARVSNWPLYCLF
Q9H6H4 S152 Sugiyama REEP4 C8orf20 PP432 AAVQAATKSQGALAGRLRsFsMQDLRSISDAPAPAyHDPLy
Q9HAU0 S410 Sugiyama PLEKHA5 KIAA1686 PEPP2 NRPNTGPLytEADRVIQRtNsMQQLEQWIKIQKGRGHEEET
Q9NQP4 S125 Sugiyama PFDN4 PFD4 VEsIQRVLADLKVQLYAKFGsNINLEADEs___________
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NWS0 S175 Sugiyama PIH1D1 NOP17 NLQLNPEWRMMKNRPFMGsIsQQNIRSEQRPRIQELGDLyt
Q9UGV2 T332 Sugiyama NDRG3 GMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQs
Q9UII2 S63 Sugiyama ATP5IF1 ATPI ATPIF1 AGGAFGKREQAEEERyFRAQsREQLAALKKHHEEEIVHHKK
Q9UPU5 S2047 Sugiyama USP24 KIAA1057 VRRRYWNAYMLFYQRVSDQNsPVLPKKSRVSVVRQEAEDLs
Q9UQ35 S1103 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sPsLQSKSQTsPKGGRsRsssPVtELAsRsPIRQDRGEFsA
Q9Y3U8 S91 Sugiyama RPL36 KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______
Q9Y450 S69 Sugiyama HBS1L HBS1 KIAA1038 sVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCLDHMR