DAPK3

All methods over the ±5 window, side by side.

PSPA

CDDM

MLP-attr

Normalized values from positional scanning peptide array

PSPA measures pT, so at flanking positions the pS row is a duplicate of the pT row. At position 0 the acceptor identity (pS, pT, pY) is genuine.

Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Position-wise Probabilities (±5 window)

Log-Odds (±5 window)

Motifs stratified by phospho-acceptor (S / T / Y)

K-means sub-motif clusters

Signed attribution PSSM distilled from the CDDM discriminative MLP (in-silico saturation mutagenesis). Letters above 0 are enriched, below are depleted; this is not a probability distribution.

MLP-attribution PSSM (±5, signed)

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substrate_uniprot	site	source	substrate_genes	site_seq
O14950	S20	GPS6\|SIGNOR\|EPSD\|PSP	MYL12B MRLC2 MYLC2B	_MSSKKAKTKTTKKRPQRAtsNVFAMFDQSQIQEFKEAFNM
O14950	T19	GPS6\|SIGNOR\|EPSD\|PSP	MYL12B MRLC2 MYLC2B	__MSSKKAKTKTTKKRPQRAtsNVFAMFDQSQIQEFKEAFN
O14974	T696	GPS6\|EPSD	PPP1R12A MBS MYPT1	EEsEsQRKARSRQARQsRRstQGVtLtDLQEAEKtIGRSRS
O43293	S311	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	DAPK3 ZIPK	KPERRRLKtTRLKEYtIKsHssLPPNNsYADFERFsKVLEE
O43293	S371	Sugiyama	DAPK3 ZIPK	EDVEALAAIYEEKEAWYREEsDSLGQDLRRLRQELLKTEAL
O43293	S407	Sugiyama	DAPK3 ZIPK	KTEALKRQAQEEAKGALLGTsGLKRRFSRLENRYEALAKQV
O43293	S50	EPSD	DAPK3 ZIPK	CRQKGTGKEYAAKFIKKRRLsSSRRGVSREEIEREVNILRE
O43293	T180	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	DAPK3 ZIPK	IDFGIAHKIEAGNEFKNIFGtPEFVAPEIVNYEPLGLEADM
O43293	T225	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	DAPK3 ZIPK	VITYILLSGASPFLGETKQEtLTNISAVNYDFDEEYFSNTS
O43293	T265	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	DAPK3 ZIPK	SELAKDFIRRLLVKDPKRRMtIAQSLEHSWIKAIRRRNVRG
O43293	T299	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	DAPK3 ZIPK	RRRNVRGEDSGRKPERRRLKtTRLKEYtIKsHssLPPNNsY
O43293	T306	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	DAPK3 ZIPK	EDSGRKPERRRLKtTRLKEYtIKsHssLPPNNsYADFERFs
O43852	Y263	Sugiyama	CALU	KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG
P00558	S415	Sugiyama	PGK1 PGKA MIG10 OK/SW-cl.110	GGGAsLELLEGKVLPGVDALsNI__________________
P00558	Y161	Sugiyama	PGK1 PGKA MIG10 OK/SW-cl.110	KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P04637	S20	SIGNOR\|EPSD\|PSP	TP53 P53	_MEEPQsDPsVEPPLsQEtFsDLWKLLPENNVLsPLPsQAM
P04792	S78	Sugiyama	HSPB1 HSP27 HSP28	LPPAAIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVs
P04792	S82	Sugiyama	HSPB1 HSP27 HSP28	AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P06733	T205	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P07205	Y161	Sugiyama	PGK2 PGKB	KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P08758	T111	Sugiyama	ANXA5 ANX5 ENX2 PP4	yDAyELKHALKGAGTNEKVLtEIIAsRtPEELRAIKQVyEE
P10809	T422	Sugiyama	HSPD1 HSP60	AVLKVGGtsDVEVNEKKDRVtDALNAtRAAVEEGIVLGGGC
P11142	T47	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtNtV
P15880	T202	Sugiyama	RPS2 RPS4	CKVTGRCGsVLVRLIPAPRGtGIVsAPVPKKLLMMAGIDDC
P17066	T49	Sugiyama	HSPA6 HSP70B'	EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P19338	S460	Sugiyama	NCL	ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P24844	S20	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MYL9 MLC2 MRLC1 MYRL2	_MssKRAKAKtTKKRPQRAtsNVFAMFDQSQIQEFKEAFNM
P24844	T19	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MYL9 MLC2 MRLC1 MYRL2	__MssKRAKAKtTKKRPQRAtsNVFAMFDQSQIQEFKEAFN
P25398	Y127	Sugiyama	RPS12	sCVVVKDYGKESQAKDVIEEyFKCKK_______________
P26038	T526	Sugiyama	MSN	EERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHA
P34931	T49	Sugiyama	HSPA1L	EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQNTV
P35579	T1745	Sugiyama	MYH9	RRLEARIAQLEEELEEEQGNtELINDRLKKANLQIDQINtD
P37802	S163	Sugiyama	TAGLN2 KIAA0120 CDABP0035	LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P38936	T145	GPS6\|SIGNOR\|iPTMNet\|EPSD\|PSP	CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1	EQAEGsPGGPGDSQGRKRRQtsMTDFYHsKRRLIFSKRKP_
P39023	S13	Sugiyama	RPL3 OK/SW-cl.32	________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P40429	S77	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	RPL13A	FLRKRMNtNPSRGPyHFRAPsRIFWRTVRGMLPHKTKRGQA
P40763	S727	GPS6	STAT3 APRF	KTKFICVtPttCsNtIDLPMsPRTLDSLMQFGNNGEGAEPS
P42677	T74	Sugiyama	RPS27 MPS1	VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
P46776	S68	Sugiyama	RPL27A	yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46783	T148	Sugiyama	RPS10	RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___
P48741	T49	Sugiyama	HSPA7 HSP70B	EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P54652	T48	Sugiyama	HSPA2	EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTNTI
P61254	T8	Sugiyama	RPL26	_____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P62277	S12	Sugiyama	RPS13	_________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62937	T157	Sugiyama	PPIA CYPA	NIVEAMERFGsRNGKTSKKItIADCGQLE____________
P63104	S28	Sugiyama	YWHAZ	QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P68431	T12	GPS6\|ELM\|iPTMNet\|EPSD	H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J	_________MARtKQtARKstGGKAPRKQLATKAARKsAPA
Q00987	S166	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	MDM2	KPSSSHLVSRPstSSRRRAIsEtEENsDELsGERQRKRHKs
Q00987	S186	EPSD\|PSP	MDM2	sEtEENsDELsGERQRKRHKsDsISLsFDESLALCVIREIC
Q07020	T136	Sugiyama	RPL18	AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q13442	T18	Sugiyama	PDAP1 HASPP28	___MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEE
Q14457	S90	EPSD\|PSP	BECN1 GT197	IETPRQDGVSRRFIPPARMMsTEsANsFTLIGEASDGGtME
Q14669	S312	PSP	TRIP12 KIAA0045 ULF	PSGLQAKLASLRKSTKKRsEsPPAELPSLRRSTRQKTTGSC
Q71UM5	T74	Sugiyama	RPS27L	VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
Q96A00	S12	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	PPP1R14A CPI17 PPP1INL	_________MAAQRLGKRVLsKLQSPSRARGPGGsPGGLQK
Q96A00	T38	EPSD\|PSP	PPP1R14A CPI17 PPP1INL	SRARGPGGsPGGLQKRHARVtVKYDRRELQRRLDVEKWIDG
Q9NQ39	T159	Sugiyama	RPS10P5 RPS10L	RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___
Q9UNH5	S484	PSP	CDC14A	TSLSSGATVRSFSINSRLAssLGNLNAATDDPENKKTSSSS
Q9UNX3	T8	Sugiyama	RPL26L1 RPL26P1	_____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9Y2B0	S74	Sugiyama	CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426	GsFRINPDGsQsVVEVPyARsEAHLtELLEEICDRMKEyGE