GRK1

All methods over the ±5 window, side by side.

PSPA

CDDM

MLP-attr

Normalized values from positional scanning peptide array

PSPA measures pT, so at flanking positions the pS row is a duplicate of the pT row. At position 0 the acceptor identity (pS, pT, pY) is genuine.

Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Position-wise Probabilities (±5 window)

Log-Odds (±5 window)

Motifs stratified by phospho-acceptor (S / T / Y)

K-means sub-motif clusters

Signed attribution PSSM distilled from the CDDM discriminative MLP (in-silico saturation mutagenesis). Letters above 0 are enriched, below are depleted; this is not a probability distribution.

MLP-attribution PSSM (±5, signed)

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substrate_uniprot	site	source	substrate_genes	site_seq
A5A3E0	S1068	Sugiyama	POTEF A26C1B	SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
O00505	S60	Sugiyama	KPNA3 QIP2	KRDEHLLKKRNVPQEEsLEDsDVDADFKAQNVTLEAILQNA
O60220	S94	Sugiyama	TIMM8A DDP DDP1 TIM8A	SQFILNRLEQTQKSKPVFSEsLsD_________________
O95394	S64	Sugiyama	PGM3 AGM1	LLAVLRSKQTKSTIGVMVtAsHNPEEDNGVKLVDPLGEMLA
O95714	S2928	Sugiyama	HERC2	ILLGRIRAEEEDLAAVPFLAsDNEEEEDEKGNSGsLIRKKA
P04075	S36	Sugiyama	ALDOA ALDA	LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075	S46	Sugiyama	ALDOA ALDA	PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04075	T37	Sugiyama	ALDOA ALDA	sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04406	S241	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04792	S82	Sugiyama	HSPB1 HSP27 HSP28	AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05386	S101	Sugiyama	RPLP1 RRP1	APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386	S104	Sugiyama	RPLP1 RRP1	tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387	S102	Sugiyama	RPLP2 D11S2243E RPP2	PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387	S105	Sugiyama	RPLP2 D11S2243E RPP2	GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05787	S291	Sugiyama	KRT8 CYK8	ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P05787	S475	Sugiyama	KRT8 CYK8	TSSSRAVVVKKIETRDGKLVsEssDVLPK____________
P07814	S747	Sugiyama	EPRS1 EPRS GLNS PARS QARS QPRS PIG32	ETSAPFKERPtPsLNNNCttsEDsLVLyNRVAVQGDVVREL
P08100	S334	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	RHO OPN2	RNCMLTTICCGKNPLGDDEAsAtVsKtETsQVAPA______
P08100	S338	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	RHO OPN2	LTTICCGKNPLGDDEAsAtVsKtETsQVAPA__________
P08100	S343	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	RHO OPN2	CGKNPLGDDEAsAtVsKtETsQVAPA_______________
P08195	S598	Sugiyama	SLC3A2 MDU1	LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP
P08238	S468	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238	S535	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	EPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
P08238	T537	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	IDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK
P0CG38	S1068	Sugiyama	POTEI	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39	S1031	Sugiyama	POTEJ	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DPH7	S48	Sugiyama	TUBA3C TUBA2	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7	S54	Sugiyama	TUBA3C TUBA2	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
P15531	S120	Sugiyama	NME1 NDPKA NM23	KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P15531	S122	Sugiyama	NME1 NDPKA NM23	GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P17987	S551	Sugiyama	TCP1 CCT1 CCTA	IKLHPESKDDKHGsyEDAVHsGALND_______________
P19338	S619	Sugiyama	NCL	RIVTDRETGssKGFGFVDFNsEEDAKAAKEAMEDGEIDGNK
P22059	S193	Sugiyama	OSBP OSBP1	VTALELAKAKAVKMLAEsDEsGDEEsVsQtDKTELQNTLRT
P25705	S53	Sugiyama	ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM	ARNFHASNTHLQKtGtAEMssILEERILGADtsVDLEETGR
P25788	S243	Sugiyama	PSMA3 HC8 PSC8	GRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM________
P25788	Y239	Sugiyama	PSMA3 HC8 PSC8	ELTNGRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM____
P29401	S295	Sugiyama	TKT	ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI
P29692	T147	Sugiyama	EEF1D EF1D	PQtQHVsPMRQVEPPAKKPAtPAEDDEDDDIDLFGsDNEEE
P30050	S138	Sugiyama	RPL12	HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050	S157	Sugiyama	RPL12	QsVGCNVDGRHPHDIIDDINsGAVECPAs____________
P35221	S641	Sugiyama	CTNNA1	GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD
P35241	S533	Sugiyama	RDX	ERVTETQKNERVKKQLQALssELAQARDETKKTQNDVLHAE
P35579	S1308	Sugiyama	MYH9	LLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLs
P38646	S89	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P41145	S358	EPSD\|PSP	OPRK1 OPRK	KRCFRDFCFPLKMRMERQSTsRVRNTVQDPAYLRDIDGMNK
P41227	S216	Sugiyama	NAA10 ARD1 ARD1A TE2	EEKGLAAEDsGGDsKDLsEVsEtTEstDVKDssEAsDsAs_
P43487	S60	Sugiyama	RANBP1	TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P49137	S272	GPS6	MAPKAPK2	IMYILLCGYPPFYSNHGLAIsPGMKTRIRMGQYEFPNPEWS
P49137	T222	GPS6	MAPKAPK2	ILKLtDFGFAKEttsHNsLttPCytPyyVAPEVLGPEKYDK
P49137	T25	GPS6	MAPKAPK2	SQGQsPPVPFPAPAPPPQPPtPALPHPPAQPPPPPPQQFPQ
P49137	T334	GPS6	MAPKAPK2	MTItEFMNHPWIMQSTKVPQtPLHtsRVLKEDKERWEDVKE
P55060	S342	Sugiyama	CSE1L CAS XPO2	ASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEAF
P55060	S366	Sugiyama	CSE1L CAS XPO2	KVIVPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAA
P56385	S66	Sugiyama	ATP5ME ATP5I ATP5K	EEKKKQDELKRIARELAEDDsILK_________________
P60709	S368	Sugiyama	ACTB	sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709	T106	Sugiyama	ACTB	WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET
P61247	S263	Sugiyama	RPS3A FTE1 MFTL	GDEtGAKVERADGyEPPVQEsV___________________
P62249	S9	Sugiyama	RPS16	____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258	S148	Sugiyama	YWHAE	YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P63104	S28	Sugiyama	YWHAZ	QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104	T30	Sugiyama	YWHAZ	AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN
P63261	S368	Sugiyama	ACTG1 ACTG	sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261	T106	Sugiyama	ACTG1 ACTG	WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET
P68363	S48	Sugiyama	TUBA1B	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363	S54	Sugiyama	TUBA1B	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q13435	S289	Sugiyama	SF3B2 SAP145	IPQALEKILQLKESRQEEMNsQQEEEEMETDARssLGQsAs
Q13561	S391	Sugiyama	DCTN2 DCTN50	LTQVQTTMRENLATVEGNFAsIDERMKKLGK__________
Q15021	T1331	Sugiyama	NCAPD2 CAPD2 CNAP1 KIAA0159	QRAPsAKKPSTGSRyQPLAstAsDNDFVtPEPRRTTRRHPN
Q15835	S21	GPS6\|SIGNOR\|iPTMNet\|EPSD	GRK1 RHOK	MDFGsLETVVANSAFIAARGsFDGSSSQPSRDKKYLAKLKL
Q15835	S491	SIGNOR\|iPTMNet\|EPSD	GRK1 RHOK	PFIPDSKTVYAKDIQDVGAFstVKGVAFDKTDTEFFQEFAT
Q15835	T492	SIGNOR\|iPTMNet\|EPSD	GRK1 RHOK	FIPDSKTVYAKDIQDVGAFstVKGVAFDKTDTEFFQEFATG
Q58FF7	S408	Sugiyama	HSP90AB3P HSP90BC	EPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
Q58FF7	T410	Sugiyama	HSP90AB3P HSP90BC	IDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK
Q58FF8	S308	Sugiyama	HSP90AB2P HSP90BB	YMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEE
Q6PEY2	S48	Sugiyama	TUBA3E	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2	S54	Sugiyama	TUBA3E	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q6S8J3	S1068	Sugiyama	POTEE A26C1A POTE2	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q71U36	S48	Sugiyama	TUBA1A TUBA3	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36	S54	Sugiyama	TUBA1A TUBA3	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q8NFD5	S1744	Sugiyama	ARID1B BAF250B DAN15 KIAA1235 OSA2	ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI
Q92973	S339	Sugiyama	TNPO1 KPNB2 MIP1 TRN	SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE
Q96HE7	S143	Sugiyama	ERO1A ERO1L UNQ434/PRO865	EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD
Q99497	S57	Sugiyama	PARK7	GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL
Q99613	S39	Sugiyama	EIF3C EIF3S8	GEELVTKPVGGNyGKQPLLLsEDEEDTKRVVRSAKDKRFEE
Q99733	S125	Sugiyama	NAP1L4 NAP2	KRREFItGDVEPtDAEsEWHsENEEEEKLAGDMKSKVVVTE
Q9BQE3	S439	Sugiyama	TUBA1C TUBA6	SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BQE3	S48	Sugiyama	TUBA1C TUBA6	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3	S54	Sugiyama	TUBA1C TUBA6	GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q9BYX7	S368	Sugiyama	POTEKP ACTBL3 FKSG30	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9H2G2	S362	Sugiyama	SLK KIAA0204 STK2	DLsIAssEEDKLsQNACILEsVSEKtERSNsEDKLNSKILN
Q9H2G2	S518	Sugiyama	SLK KIAA0204 STK2	tVDLVSQEtGEKEANIQAVDsEVGLTKEDtQEKLGEDDKTQ
Q9Y5S9	S56	Sugiyama	RBM8A RBM8 HSPC114 MDS014	KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF