GRK3

All methods over the ±5 window, side by side.
PSPA
CDDM
MLP-attr
Normalized values from positional scanning peptide array
PSPA measures pT, so at flanking positions the pS row is a duplicate of the pT row. At position 0 the acceptor identity (pS, pT, pY) is genuine.
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Position-wise Probabilities (±5 window)
Log-Odds (±5 window)
Motifs stratified by phospho-acceptor (S / T / Y)
K-means sub-motif clusters
Signed attribution PSSM distilled from the CDDM discriminative MLP (in-silico saturation mutagenesis). Letters above 0 are enriched, below are depleted; this is not a probability distribution.
MLP-attribution PSSM (±5, signed)
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substrate_uniprot site source substrate_genes site_seq
O95394 S64 Sugiyama PGM3 AGM1 LLAVLRSKQTKSTIGVMVtAsHNPEEDNGVKLVDPLGEMLA
P07550 S355 ELM|EPSD|PSP ADRB2 ADRB2R B2AR AFQELLCLRRssLKAyGNGyssNGNtGEQsGYHVEQEKENK
P07550 S356 ELM|EPSD|PSP ADRB2 ADRB2R B2AR FQELLCLRRssLKAyGNGyssNGNtGEQsGYHVEQEKENKL
P08172 S232 ELM CHRM2 ASKSRIKKDKKEPVANQDPVsPsLVQGRIVKPNNNNMPssD
P08172 S234 ELM CHRM2 KSRIKKDKKEPVANQDPVsPsLVQGRIVKPNNNNMPssDDG
P08172 S250 ELM CHRM2 PVsPsLVQGRIVKPNNNNMPssDDGLEHNKIQNGKAPRDPV
P08172 S251 ELM CHRM2 VsPsLVQGRIVKPNNNNMPssDDGLEHNKIQNGKAPRDPVt
P08172 S282 ELM CHRM2 NGKAPRDPVtENCVQGEEKEssNDstsVsAVAsNMRDDEIt
P08172 S283 ELM CHRM2 GKAPRDPVtENCVQGEEKEssNDstsVsAVAsNMRDDEItQ
P08172 S286 ELM CHRM2 PRDPVtENCVQGEEKEssNDstsVsAVAsNMRDDEItQDEN
P08172 S288 ELM CHRM2 DPVtENCVQGEEKEssNDstsVsAVAsNMRDDEItQDENtV
P08172 S290 ELM CHRM2 VtENCVQGEEKEssNDstsVsAVAsNMRDDEItQDENtVst
P08172 S294 ELM CHRM2 CVQGEEKEssNDstsVsAVAsNMRDDEItQDENtVstsLGH
P08172 S309 ELM CHRM2 VsAVAsNMRDDEItQDENtVstsLGHSKDENSKQTCIRIGT
P08172 S311 ELM CHRM2 AVAsNMRDDEItQDENtVstsLGHSKDENSKQTCIRIGTKT
P08172 T271 ELM CHRM2 sDDGLEHNKIQNGKAPRDPVtENCVQGEEKEssNDstsVsA
P08172 T287 ELM CHRM2 RDPVtENCVQGEEKEssNDstsVsAVAsNMRDDEItQDENt
P08172 T302 ELM CHRM2 ssNDstsVsAVAsNMRDDEItQDENtVstsLGHSKDENSKQ
P08172 T307 ELM CHRM2 tsVsAVAsNMRDDEItQDENtVstsLGHSKDENSKQTCIRI
P08172 T310 ELM CHRM2 sAVAsNMRDDEItQDENtVstsLGHSKDENSKQTCIRIGTK
P21731 S239 SIGNOR|PSP TBXA2R VATLCHVYHGQEAAQQRPRDsEVEMMAQLLGIMVVASVCWL
P30411 S366 SIGNOR BDKRB2 BKR2 VyQGVCQKGGCRSEPIQMENsMGTLRTsIsVERQIHKLQDW
P30411 S373 SIGNOR BDKRB2 BKR2 KGGCRSEPIQMENsMGTLRTsIsVERQIHKLQDWAGSRQ__
P30411 S375 SIGNOR BDKRB2 BKR2 GCRSEPIQMENsMGTLRTsIsVERQIHKLQDWAGSRQ____
P30874 S341 EPSD|PSP SSTR2 KSFQNVLCLVKVSGTDDGERsDsKQDKSRLNEttEtQRtLL
P30874 S343 EPSD|PSP SSTR2 FQNVLCLVKVSGTDDGERsDsKQDKSRLNEttEtQRtLLNG
P32245 S329 ELM MC4R LRKtFKEIICCYPLGGLCDLssRY_________________
P32245 S330 ELM MC4R RKtFKEIICCYPLGGLCDLssRY__________________
P32245 T312 ELM MC4R MCNSIIDPLIYALRSQELRKtFKEIICCYPLGGLCDLssRY
P35372 T182 SIGNOR OPRM1 MOR1 TMSVDRyIAVCHPVKALDFRtPRNAKIINVCNWILSSAIGL
P41143 S363 PSP OPRD1 OPRD SsFSRAREATARERVtACtPsDGPGGGAAA___________
P41143 T361 PSP OPRD1 OPRD DPSsFSRAREATARERVtACtPsDGPGGGAAA_________
P41146 S346 PSP OPRL1 OOR ORL1 FKACFRKFCCASALRRDVQVsDRVRsIAKDVALACKtsETV
P41146 S351 PSP OPRL1 OOR ORL1 RKFCCASALRRDVQVsDRVRsIAKDVALACKtsETVPRPA_
P41146 S363 EPSD|PSP OPRL1 OOR ORL1 VQVsDRVRsIAKDVALACKtsETVPRPA_____________
P41146 T362 PSP OPRL1 OOR ORL1 DVQVsDRVRsIAKDVALACKtsETVPRPA____________
P51681 S336 GPS6|SIGNOR|ELM|EPSD|PSP CCR5 CMKBR5 IAKRFCKCCSIFQQEAPERAssVyTRsTGEQEIsVGL____
P51681 S337 GPS6|SIGNOR|ELM|EPSD|PSP CCR5 CMKBR5 AKRFCKCCSIFQQEAPERAssVyTRsTGEQEIsVGL_____
P51681 S342 GPS6|SIGNOR|ELM|EPSD|PSP CCR5 CMKBR5 KCCSIFQQEAPERAssVyTRsTGEQEIsVGL__________
P51681 S349 GPS6|SIGNOR|ELM|EPSD|PSP CCR5 CMKBR5 QEAPERAssVyTRsTGEQEIsVGL_________________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q08J23 S593 Sugiyama NSUN2 SAKI TRM4 NNSEKMKVINTGIKVWCRNNsGEEFDCAFRLAQEGIYTLYP
Q6ZMQ8 T784 Sugiyama AATK AATYK KIAA0641 LMR1 LMTK1 SWTETASSGGDHPQAEPKLAtEAEGTTGPRLPLPSVPSPSQ
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI