HIPK3

All methods over the ±5 window, side by side.
PSPA
CDDM
MLP-attr
Normalized values from positional scanning peptide array
PSPA measures pT, so at flanking positions the pS row is a duplicate of the pT row. At position 0 the acceptor identity (pS, pT, pY) is genuine.
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Position-wise Probabilities (±5 window)
Log-Odds (±5 window)
Motifs stratified by phospho-acceptor (S / T / Y)
K-means sub-motif clusters
Signed attribution PSSM distilled from the CDDM discriminative MLP (in-silico saturation mutagenesis). Letters above 0 are enriched, below are depleted; this is not a probability distribution.
MLP-attribution PSSM (±5, signed)
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substrate_uniprot site source substrate_genes site_seq
O00115 S70 Sugiyama DNASE2 DNASE2A DNL2 QYKyLDEssGGWRDGRALINsPEGAVGRSLQPLyRSNTSQL
O00165 S153 Sugiyama HAX1 HS1BP1 PDSHQPRIFGGVLESDARSEsPQPAPDWGsQRPFHRFDDVW
O15047 S470 Sugiyama SETD1A KIAA0339 KMT2F SET1 SET1A sPEREEVRtsPRPAsPARsGsPAPEttNESVPFAQHSSLDS
O43488 S40 Sugiyama AKR7A2 AFAR AFAR1 AKR7 SPPPEARALAMSRPPPPRVAsVLGTMEMGRRMDAPAsAAAV
O43765 T81 Sugiyama SGTA SGT SGT1 IFEAAATGKEMPQDLRsPARtPPsEEDsAEAERLKTEGNEQ
O60716 S252 Sugiyama CTNND1 KIAA0384 sRVtRIEERyRPsMEGyRAPsRQDVyGPQPQVRVGGssVDL
O76080 S48 Sugiyama ZFAND5 ZA20D2 ZNF216 GMCSVCYKEHLQRQQNsGRMsPMGtAsGsNsPtsDSASVQR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 T37 Sugiyama ALDOA ALDA sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 S320 Sugiyama LDHB GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______
P07437 S168 Sugiyama TUBB TUBB5 OK/SW-cl.56 GTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
P07437 S172 Sugiyama TUBB TUBB5 OK/SW-cl.56 ISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSVHQL
P07737 S30 Sugiyama PFN1 NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV
P14618 S37 Sugiyama PKM OIP3 PK2 PK3 PKM2 QLHAAMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRs
P15531 S120 Sugiyama NME1 NDPKA NM23 KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P17812 S575 Sugiyama CTPS1 CTPS LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____
P22626 S189 Sugiyama HNRNPA2B1 HNRPA2B1 IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27824 S362 Sugiyama CANX WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK
P29401 S295 Sugiyama TKT ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI
P29401 T287 Sugiyama TKT AEQIIQEIysQIQsKKKILAtPPQEDAPsVDIANIRMPsLP
P30086 S52 Sugiyama PEBP1 PBP PEBP AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P35269 T389 Sugiyama GTF2F1 RAP74 PPKRERKPsGGSSRGNsRPGtPsAEGGstsstLRAAASKLE
P35611 S12 Sugiyama ADD1 ADDA _________MNGDsRAAVVtsPPPttAPHKERyFDRVDENN
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646 T87 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKR
P42166 S158 Sugiyama TMPO LAP2 tRKLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsN
P42166 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDs
P42167 S158 Sugiyama TMPO LAP2 TRKLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSN
P42167 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSNDS
P47712 S724 Sugiyama PLA2G4A CPLA2 PLA2G4 NIDVIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFL
P47712 S727 Sugiyama PLA2G4A CPLA2 PLA2G4 VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP
P55036 S242 Sugiyama PSMD4 MCB1 VSMEEQRQRQEEEARRAAAAsAAEAGIATTGtEDsDDALLK
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263 T133 Sugiyama RPS14 PRO2640 QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
Q00613 S363 Sugiyama HSF1 HSTF1 AsVTALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNE
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q13112 S410 Sugiyama CHAF1B CAF1A CAF1P60 MPHOSPH7 MPP7 LNMRtPDtAKKTKsQtHRGssPGPRPVEGtPASRtQDPssP
Q13158 S194 GPS6|SIGNOR|ELM|iPTMNet|EPSD FADD MORT1 GIG3 ADLVQEVQQARDLQNRsGAMsPMsWNsDAsTSEAS______
Q13283 S231 Sugiyama G3BP1 G3BP QEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsW
Q13428 T1014 Sugiyama TCOF1 ARssssEsEDEDVIPAtQCLtPGIRTNVVTMPTAHPRIAPK
Q13509 S168 Sugiyama TUBB3 TUBB4 GTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
Q13509 S172 Sugiyama TUBB3 TUBB4 ISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSIHQL
Q14157 S477 Sugiyama UBAP2L KIAA0144 NICE4 PsKstsAPQMsPGssDNQsssPQPAQQKLKQQKKKAsLTSK
Q14160 S1448 Sugiyama SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL QEDEQPPWAsPsPtsRQsPAsPPPLGGGAPVRTAKAERRHQ
Q14160 S1486 Sugiyama SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL RHQERLRVQsPEPPAPERALsPAELRALEAEKRALWRAARM
Q14160 S1541 Sugiyama SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL SRsQEGRGTRGPLERLAEAPsPAPtPsPtPVEDLGPQtsts
Q14160 T1545 Sugiyama SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL EGRGTRGPLERLAEAPsPAPtPsPtPVEDLGPQtstsPGRL
Q14247 T401 Sugiyama CTTN EMS1 RQEQEEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVy
Q14258 S100 Sugiyama TRIM25 EFP RNF147 ZNF147 DLAREPPADVWtPPARAsAPsPNAQVACDHCLKEAAVKTCL
Q15080 S67 Sugiyama NCF4 SH3PXD4 TKGGSKYLIYRRYRQFHALQsKLEERFGPDSKSSALACTLP
Q15637 S82 Sugiyama SF1 ZFM1 ZNF162 TRKLRtGDLGIPPNPEDRsPsPEPIyNsEGKRLNTREFRTR
Q4KMP7 S28 Sugiyama TBC1D10B FP2461 LVAPPRRHGAPAAPsPPPRGsRAGPVVVVAPGPPVTTATSA
Q53EL6 T93 Sugiyama PDCD4 H731 RGDsVsDsGsDALRSGLtVPtsPKGRLLDRRSRSGKGRGLP
Q7Z2W4 T273 Sugiyama ZC3HAV1 ZC3HDC2 PRO1677 FFQGsQEFLASASAsAERsCtPsPDQIsHRAsLEDAPVDDL
Q7Z460 S253 Sugiyama CLASP1 KIAA0622 MAST1 IQSANDKNFDDEDsVDGNRPssAsStSSKAPPSSRRNVGMG
Q86UE4 S411 Sugiyama MTDH AEG1 LYRIC NSDWNAPAEEWGNWVDEERAsLLKsQEPIPDDQKVsDDDKE
Q86UE4 S415 Sugiyama MTDH AEG1 LYRIC NAPAEEWGNWVDEERAsLLKsQEPIPDDQKVsDDDKEKGEG
Q86YP4 S100 Sugiyama GATAD2A DGPVDMRTSHSDMKSERRPPsPDVIVLsDNEQPssPRVNGL
Q86Z02 S342 Sugiyama HIPK1 KIAA0630 MYAK NBAK2 MLVDPVRQPYRVKVIDFGSAsHVSKAVCstyLQsRYYRAPE
Q8IWW6 S240 Sugiyama ARHGAP12 SSSsTEQIRAttPPNQGRPDsPVyANLQELKISQSALPPLP
Q8IWW6 T231 Sugiyama ARHGAP12 QDSEsGDELSSSsTEQIRAttPPNQGRPDsPVyANLQELKI
Q8IWX8 S815 Sugiyama CHERP DAN26 SCAF6 RSQSRSRSKSYSPGRRRRsRsRsPtPPssAGLGsNsAPPIP
Q8IWX8 S817 Sugiyama CHERP DAN26 SCAF6 QSRSRSKSYSPGRRRRsRsRsPtPPssAGLGsNsAPPIPDS
Q8IZ21 S118 Sugiyama PHACTR4 PRO2963 PSDAMLKNGHTTPIGNARsssPVQVEEEPVRLAsLRKAIPE
Q8N684 T203 Sugiyama CPSF7 GGIPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLP
Q8WXI9 S122 Sugiyama GATAD2B KIAA1150 DEPVDMSARRsEPERGRLtPsPDIIVLsDNEAssPRsSsRM
Q8WXI9 T120 Sugiyama GATAD2B KIAA1150 INDEPVDMSARRsEPERGRLtPsPDIIVLsDNEAssPRsSs
Q96MH2 S76 Sugiyama HEXIM2 L3 EDLAGAVGGLGWNsRsPRtQsPGGCsAEAVLARKKHRRRPS
Q9C0C2 S1103 Sugiyama TNKS1BP1 KIAA1741 TAB182 KRGWVGEFSLSVGPQREAAFsPGQQDWsRDFCIEASERsyQ
Q9C0C2 S504 Sugiyama TNKS1BP1 KIAA1741 TAB182 PSGLGVWRLDsPPPsPItEAsEAAEAAEAGNLAVSSREEGV
Q9C0C2 S672 Sugiyama TNKS1BP1 KIAA1741 TAB182 TLARAETtQARtEAQDLCRAsPEPPGPEsSSRWLDDLLAsP
Q9H2X6 S351 Sugiyama HIPK2 MLVDPSRQPYRVKVIDFGSAsHVSKAVCstyLQsRYyRAPE
Q9H422 S349 Sugiyama HIPK3 DYRK6 FIST3 PKY MLVDPVRQPYRVKVIDFGSAsHVSKTVCstyLQsRYYRAPE
Q9H422 S362 Sugiyama HIPK3 DYRK6 FIST3 PKY VIDFGSAsHVSKTVCstyLQsRYYRAPEIILGLPFCEAIDM
Q9H422 T177 Sugiyama HIPK3 DYRK6 FIST3 PKY NMGNPVTVVTATTGSKQNCTtGEGDYQLVQHEVLCSMKNTY
Q9H422 T250 Sugiyama HIPK3 DYRK6 FIST3 PKY NHPSYARQGQIEVSILARLStENADEYNFVRAYECFQHRNH
Q9H422 Y359 Sugiyama HIPK3 DYRK6 FIST3 PKY RVKVIDFGSAsHVSKTVCstyLQsRYYRAPEIILGLPFCEA
Q9HC35 S146 Sugiyama EML4 C2orf2 EMAPL4 REKKEEsHsNDQsPQIRAsPsPQPssQPLQIHRQtPEsKNA
Q9NPI6 S523 Sugiyama DCP1A SMIF APSVFQQTVTRSSDLERKAssPsPLtIGtPEsQRKPSIILS
Q9NTJ3 T44 Sugiyama SMC4 CAPC SMC4L1 DGAssDAEPEPPsGRtEsPAtAAEtAsEELDNRSLEEILNS
Q9UER7 S668 PSP DAXX BING2 DAP6 YVERQRSVHEKNGKKICtLPsPPsPLAsLAPVADsstRVDs
Q9UHI6 T705 Sugiyama DDX20 DP103 GEMIN3 sEstPVDDRIsLEQPPNGsDtPNPEKyQEsPGIQMKTRLKE
Q9UPQ0 S217 Sugiyama LIMCH1 KIAA1102 GRDDsFDsLDsFGsRsRQtPsPDVVLRGssDGRGsDsEsDL
Q9UPQ0 T215 Sugiyama LIMCH1 KIAA1102 RHGRDDsFDsLDsFGsRsRQtPsPDVVLRGssDGRGsDsEs
Q9UQ35 S1103 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sPsLQSKSQTsPKGGRsRsssPVtELAsRsPIRQDRGEFsA
Q9UQ35 S2132 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 SRMsCFsRPsMsPtPLDRCRsPGMLEPLGssRtPMsVLQQA
Q9UQ35 S2398 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 ANLtsPRVPLsAyERVsGRtsPPLLDRARsRtPPsAPsQsR