MPSK1

All methods over the ±5 window, side by side.
PSPA
CDDM
MLP-attr
Normalized values from positional scanning peptide array
PSPA measures pT, so at flanking positions the pS row is a duplicate of the pT row. At position 0 the acceptor identity (pS, pT, pY) is genuine.
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Position-wise Probabilities (±5 window)
Log-Odds (±5 window)
Motifs stratified by phospho-acceptor (S / T / Y)
K-means sub-motif clusters
Signed attribution PSSM distilled from the CDDM discriminative MLP (in-silico saturation mutagenesis). Letters above 0 are enriched, below are depleted; this is not a probability distribution.
MLP-attribution PSSM (±5, signed)
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substrate_uniprot site source substrate_genes site_seq
O15085 S1295 Sugiyama ARHGEF11 KIAA0380 PEQEDMGLCSLEHLPPRtRNsGIWEsPELDRNLAEDASSTE
O15085 T1292 Sugiyama ARHGEF11 KIAA0380 GERPEQEDMGLCSLEHLPPRtRNsGIWEsPELDRNLAEDAS
O15371 T46 Sugiyama EIF3D EIF3S7 RDMPyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGG
O43390 T134 Sugiyama HNRNPR HNRPR KVQESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDS
O43390 T142 Sugiyama HNRNPR HNRPR PDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGVQPG
O60506 T131 Sugiyama SYNCRIP HNRPQ NSAP1 KVADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDS
O60506 T139 Sugiyama SYNCRIP HNRPQ NSAP1 PDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGQQPs
O75716 S197 GPS6|SIGNOR|EPSD|PSP STK16 MPSK1 PKL12 TSF1 VEGSRQALtLQDWAAQRCTIsyRAPELFSVQSHCVIDERTD
O75716 T185 GPS6|SIGNOR|EPSD|PSP STK16 MPSK1 PKL12 TSF1 MDLGSMNQACIHVEGSRQALtLQDWAAQRCTIsyRAPELFS
O75716 Y198 SIGNOR|EPSD|PSP STK16 MPSK1 PKL12 TSF1 EGSRQALtLQDWAAQRCTIsyRAPELFSVQSHCVIDERTDV
O96019 T72 Sugiyama ACTL6A BAF53 BAF53A INO80K TLMEIDGDKGKQGGPtyyIDtNALRVPRENMEAIsPLKNGM
P00491 S163 Sugiyama PNP NP GQNPLRGPNDERFGDRFPAMsDAyDRtMRQRALstWKQMGE
P00966 T208 Sugiyama ASS1 ASS IsyEAGILENPKNQAPPGLytKtQDPAKAPNtPDILEIEFK
P04040 T29 Sugiyama CAT SDQMQHWKEQRAAQKADVLttGAGNPVGDKLNVItVGPRGP
P04075 T37 Sugiyama ALDOA ALDA sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04083 S201 Sugiyama ANXA1 ANX1 LPC1 LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P07437 T55 Sugiyama TUBB TUBB5 OK/SW-cl.56 tyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDs
P07900 S50 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL
P08195 T599 Sugiyama SLC3A2 MDU1 QASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEPH
P08238 S45 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 T89 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG
P08865 T94 Sugiyama RPSA LAMBR LAMR1 VsVIssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQA
P09382 S63 Sugiyama LGALS1 CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P14625 S106 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625 T519 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 DHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIy
P14625 T522 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 NRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMA
P14625 T675 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 sGNMERIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIR
P15259 T96 Sugiyama PGAM2 PGAMM QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQVKIWR
P17066 T47 Sugiyama HSPA6 HSP70B' RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P18669 T96 Sugiyama PGAM1 PGAMA CDABP0006 QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR
P19338 T464 Sugiyama NCL KTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWsGE
P20290 T182 Sugiyama BTF3 NACB OK/SW-cl.8 LRRLAEALPKQsVDGKAPLAtGEDDDDEVPDLVENFDEAsK
P20618 Y158 Sugiyama PSMB1 PSC5 IGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLD
P22626 S225 Sugiyama HNRNPA2B1 HNRPA2B1 GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P27448 S42 Sugiyama MARK3 CTAK1 EMK2 GDGRQEVTSRTSRSGARCRNsIAsCADEQPHIGNyRLLKTI
P27448 S45 Sugiyama MARK3 CTAK1 EMK2 RQEVTSRTSRSGARCRNsIAsCADEQPHIGNyRLLKTIGKG
P29692 S162 Sugiyama EEF1D EF1D AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY
P29692 S70 Sugiyama EEF1D EF1D IARARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVE
P30041 T48 Sugiyama PRDX6 AOP2 KIAA0106 FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL
P30050 S157 Sugiyama RPL12 QsVGCNVDGRHPHDIIDDINsGAVECPAs____________
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P35269 S449 Sugiyama GTF2F1 RAP74 PQsLsGKstPQPPsGKttPNsGDVQVTEDAVRRYLTRKPMT
P35611 T16 Sugiyama ADD1 ADDA _____MNGDsRAAVVtsPPPttAPHKERyFDRVDENNPEyL
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P38646 T111 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VAFtADGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDP
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P43243 S188 Sugiyama MATR3 KIAA0723 EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P47712 S454 Sugiyama PLA2G4A CPLA2 PLA2G4 ssDsDDEsHEPKGtENEDAGsDyQsDNQASWIHRMIMALVS
P48643 T269 Sugiyama CCT5 CCTE KIAA0098 AILTCPFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMI
P48741 T47 Sugiyama HSPA7 HSP70B RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P49411 T276 Sugiyama TUFM DLEKPFLLPVEAVYSVPGRGtVVTGTLERGILKKGDECELL
P50990 T286 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 MNFsKGEENLMDAQVKAIADtGANVVVtGGKVADMALHYAN
P53621 S266 Sugiyama COPA RGHyNNVSCAVFHPRQELILsNsEDKSIRVWDMSKRTGVQT
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61978 S81 Sugiyama HNRNPK HNRPK GGKNIKALRtDyNAsVsVPDssGPERILsISADIETIGEIL
P62191 T230 Sugiyama PSMC1 yyEEMGIKPPKGVILyGPPGtGKTLLAKAVANQTsATFLRV
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62263 S137 Sugiyama RPS14 PRO2640 RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62942 T28 Sugiyama FKBP1A FKBP1 FKBP12 IsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPFK
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P78371 T242 Sugiyama CCT2 99D8.1 CCTB KKIGVNQPKRIENAKILIANtGMDtDKIKIFGsRVRVDstA
Q00613 S363 Sugiyama HSF1 HSTF1 AsVTALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNE
Q12805 S382 Sugiyama EFEMP1 FBLN3 FBNL RNPCQDPyILTPENRCVCPVsNAMCRELPQSIVYKYMSIRS
Q13247 S303 Sugiyama SRSF6 SFRS6 SRP55 ENGKGDIKsKSRsRsQsRsNsPLPVPPsKARsVsPPPKRAT
Q13283 S232 Sugiyama G3BP1 G3BP EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA
Q14568 S50 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL
Q14847 T104 Sugiyama LASP1 MLN50 VRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsNIKyHE
Q16543 T370 Sugiyama CDC37 CDC37A EAKEGEEAGPGDPLLEAVPKtGDEKDVsV____________
Q562R1 T107 Sugiyama ACTBL2 WYHTFYNELRVAPDEHPILLtEAPLNPKINREKMTQIMFEA
Q6PKG0 T747 Sugiyama LARP1 KIAA0731 LARP PPVDPNQEVPPGPPRFQQVPtDALANKLFGAPEPstIARsL
Q8IZ73 T407 Sugiyama RPUSD2 C15orf19 PIYNSVAWGPSRGRGGYIPKtNEELLRDLVAEHQAKQSLDV
Q8N0Y7 T96 Sugiyama PGAM4 PGAM3 QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR
Q8NFD5 S1744 Sugiyama ARID1B BAF250B DAN15 KIAA1235 OSA2 ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI
Q92615 S589 Sugiyama LARP4B KIAA0217 LARP5 ADAsVNtLPVVVSREPsVPAsCAVsAtyERsPsPAHLPDDP
Q9BQE3 S439 Sugiyama TUBA1C TUBA6 SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BX95 S112 Sugiyama SGPP1 SPP1 GLAAELGPAsPRRAGALRRNsLtGEEGQLARVSNWPLYCLF
Q9H7N4 S498 Sugiyama SCAF1 SFRS19 SRA1 GGLDLRRKILTQRRERyRQRsPsPAPAPAPAAAAGPPTRKK
Q9H7N4 S500 Sugiyama SCAF1 SFRS19 SRA1 LDLRRKILTQRRERyRQRsPsPAPAPAPAAAAGPPTRKKSR
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UQ35 S2132 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 SRMsCFsRPsMsPtPLDRCRsPGMLEPLGssRtPMsVLQQA
Q9Y285 T504 Sugiyama FARSA FARS FARSL FARSLA LQMVYDsPLCRLDAEPRPPPtQEAA________________
Q9Y295 T100 GPS6|SIGNOR DRG1 NEDD3 LLSNLAGVYSEVAAYEFTTLttVPGVIRYKGAKIQLLDLPG
Q9Y295 T101 PSP DRG1 NEDD3 LSNLAGVYSEVAAYEFTTLttVPGVIRYKGAKIQLLDLPGI