ULK1

All methods over the ±5 window, side by side.

PSPA

CDDM

MLP-attr

Normalized values from positional scanning peptide array

PSPA measures pT, so at flanking positions the pS row is a duplicate of the pT row. At position 0 the acceptor identity (pS, pT, pY) is genuine.

Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Position-wise Probabilities (±5 window)

Log-Odds (±5 window)

Motifs stratified by phospho-acceptor (S / T / Y)

K-means sub-motif clusters

Signed attribution PSSM distilled from the CDDM discriminative MLP (in-silico saturation mutagenesis). Letters above 0 are enriched, below are depleted; this is not a probability distribution.

MLP-attribution PSSM (±5, signed)

Download

substrate_uniprot	site	source	substrate_genes	site_seq
A2RUS2	S472	SIGNOR\|EPSD\|PSP	DENND3 KIAA0870	EKRASRKSSHLHVTHRRMVVsMPNLQDIAMPELAPRNssLR
A2RUS2	S490	SIGNOR\|EPSD\|PSP	DENND3 KIAA0870	VVsMPNLQDIAMPELAPRNssLRLTDTAGCRGssAVLNVtP
O00560	S6	EPSD\|PSP	SDCBP MDA9 SYCL	_______________MsLyPsLEDLKVDKVIQAQTAFSANP
O00560	S60	PSP	SDCBP MDA9 SYCL	PHDGNLyPRLyPELsQyMGLsLNEEEIRANVAVVsGAPLQG
O15027	S846	PSP	SEC16A KIAA0310 SEC16 SEC16L	PPVLIAQPDHSYNLAQPINFsVSLSNSHEKNQSWREALVGD
O60238	S35	PSP	BNIP3L BNIP3A BNIP3H NIX	NNNNCEENEQSLPPPAGLNssWVELPMNSSNGNDNGNGKNG
O60260	S108	GPS6\|PSP	PRKN PARK2	PRNAAGGCEREPQsLTRVDLsssVLPGDSVGLAVILHTDsR
O75143	S355	EPSD\|PSP	ATG13 KIAA0652	DRTHCAAtPSSSEDTEtVsNssEGRAsPHDVLETIFVRKVG
O75143	S389	PSP	ATG13 KIAA0652	IFVRKVGAFVNKPINQVTLTsLDIPFAMFAPKNLELEDTDP
O75385	S317	PSP	ULK1 KIAA0722	ssGSGSSSSSSSTSHLASPPsLGEMQQLQKTLAsPADTAGF
P06733	S115	SIGNOR\|EPSD\|PSP	ENO1 ENO1L1 MBPB1 MPB1	IEMDGtENKsKFGANAILGVsLAVCKAGAVEKGVPLyRHIA
P06733	S282	SIGNOR\|EPSD\|PSP	ENO1 ENO1L1 MBPB1 MPB1	KsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDDWG
P08235	S843	PSP	NR3C2 MCR MLR	NSQFLYFAPDLVFNEEKMHQsAMYELCQGMHQISLQFVRLQ
P08237	S74	SIGNOR\|EPSD\|PSP	PFKM PFKX	GYQGLVDGGDHIKEATWESVsMMLQLGGTVIGSARCKDFRE
P08237	S762	SIGNOR\|EPSD\|PSP	PFKM PFKX	WLKLRPILKILAKYEIDLDTsDHAHLEHITRKRSGEAAV__
P09467	S63	SIGNOR\|EPSD\|PSP	FBP1 FBP	KAISSAVRKAGIAHLYGIAGsTNVTGDQVKKLDVLSNDLVM
P09467	S88	SIGNOR\|EPSD\|PSP	FBP1 FBP	GDQVKKLDVLSNDLVMNMLKsSFATCVLVSEEDKHAIIVEP
P19367	S124	SIGNOR\|EPSD\|PSP	HK1	NVHMESEVYDTPENIVHGSGsQLFDHVAECLGDFMEKRKIK
P19367	S364	SIGNOR\|EPSD\|PSP	HK1	KNKEGLHNAKEILTRLGVEPsDDDCVSVQHVCTIVSFRSAN
P46937	S227	SIGNOR\|PSP	YAP1 YAP65	LSQMNVTAPTsPPVQQNMMNsASGPLPDGWEQAMTQDGEIY
P58004	S254	PSP	SESN2 Hi95 SEST2	PSEQSSPPSRDPLNNsGGFEsARDVEALMERMQQLQESLLR
P58004	S73	PSP	SESN2 Hi95 SEST2	VLREGAESLEQHLGLEALMSsGRVDNLAVVMGLHPDYFTSF
Q12983	S17	PSP	BNIP3 NIP3	____MSQNGAPGMQEESLQGsWVELHFsNNGNGGSVPAsVS
Q12983	S35	GPS6	BNIP3 NIP3	QGsWVELHFsNNGNGGSVPAsVSIYNGDMEKILLDAQHESG
Q13045	S64	PSP	FLII FLIL	GLCYLPEELAALQKLEHLSVsHNNLTTLHGELSSLPSLRAI
Q13546	S262	PSP	RIPK1 RIP RIP1	KSGNRPDVDDITEYCPREIIsLMKLCWEANPEARPTFPGIE
Q13546	S291	PSP	RIPK1 RIP RIP1	NPEARPTFPGIEEKFRPFYLsQLEEsVEEDVKSLKKEYSNE
Q13546	S296	PSP	RIPK1 RIP RIP1	PTFPGIEEKFRPFYLsQLEEsVEEDVKSLKKEYSNENAVVK
Q13546	S320	PSP	RIPK1 RIP RIP1	DVKSLKKEYSNENAVVKRMQsLQLDCVAVPssRsNsAtEQP
Q13546	S333	PSP	RIPK1 RIP RIP1	AVVKRMQsLQLDCVAVPssRsNsAtEQPGSLHssQGLGMGP
Q13546	S335	PSP	RIPK1 RIP RIP1	VKRMQsLQLDCVAVPssRsNsAtEQPGSLHssQGLGMGPVE
Q13546	S345	PSP	RIPK1 RIP RIP1	CVAVPssRsNsAtEQPGSLHssQGLGMGPVEEsWFAPSLEH
Q13546	S346	PSP	RIPK1 RIP RIP1	VAVPssRsNsAtEQPGSLHssQGLGMGPVEEsWFAPSLEHP
Q13546	S357	PSP	RIPK1 RIP RIP1	tEQPGSLHssQGLGMGPVEEsWFAPSLEHPQEENEPSLQSK
Q13546	S389	PSP	RIPK1 RIP RIP1	ENEPSLQSKLQDEANyHLyGsRMDRQTKQQPRQNVAYNREE
Q13546	T337	PSP	RIPK1 RIP RIP1	RMQsLQLDCVAVPssRsNsAtEQPGSLHssQGLGMGPVEEs
Q14457	S15	PSP	BECN1 GT197	______MEGSKTSNNSTMQVsFVCQRCSQPLKLDTsFKILD
Q14457	S279	PSP	BECN1 GT197	TQLDKLKKTNVFNATFHIWHsGQFGTINNFRLGRLPsVPVE
Q14457	S30	PSP	BECN1 GT197	STMQVsFVCQRCSQPLKLDTsFKILDRVTIQELTAPLLTTA
Q14457	S337	PSP	BECN1 GT197	LANKMGLKFQRYRLVPyGNHsYLESLTDKSKELPLyCSGGL
Q14457	S96	PSP	BECN1 GT197	DGVSRRFIPPARMMsTEsANsFTLIGEASDGGtMENLSRRL
Q15436	S207	EPSD\|PSP	SEC23A	YVFRGTKDLSAKQLQEMLGLsKVPLTQATRGPQVQQPPPSN
Q15436	T405	EPSD\|PSP	SEC23A	TFQRVFTKDMHGQFKMGFGGtLEIKTSREIKISGAIGPCVS
Q15437	S186	SIGNOR\|PSP	SEC23B	LITFGRMVQVHELSCEGISKsYVFRGTKDLTAKQIQDMLGL
Q16543	S339	EPSD\|PSP	CDC37 CDC37A	DAISKMDPTDAKYHMQRCIDsGLWVPNSKASEAKEGEEAGP
Q676U5	S278	PSP	ATG16L1 APG16L UNQ9393/PRO34307	RAISRAATKRLsQPAGGLLDsITNIFGRRsVssFPVPQDNV
Q6ZNE5	S29	PSP	ATG14 ATG14L KIAA0831	ARALEAPGCGPRPLARDLVDsVDDAEGLYVAVERCPLCNTT
Q7Z3C6	S14	SIGNOR\|EPSD\|PSP	ATG9A APG9L1	_______MAQFDTEyQRLEAsysDsPPGEEDLLVHVAEGSK
Q7Z3C6	S761	SIGNOR\|EPSD\|PSP	ATG9A APG9L1	sAPDEGGEGARAPQSIPRsAsYPCAAPRPGAPETTALHGGF
Q86WV6	S366	EPSD\|PSP	STING1 ERIS MITA STING TMEM173	LKTSAVPSTsTMsQEPELLIsGMEKPLPLRTDFS_______
Q8IVP5	S17	SIGNOR\|PSP	FUNDC1	____MATRNPPPQDyEsDDDsyEVLDLTEYARRHQWWNRVF
Q8N122	S792	EPSD\|PSP	RPTOR KIAA1303 RAPTOR	PENEEHILSFETIDKMRRAssYSSLNSLIGVSFNSVYTQIW
Q8N122	S855	EPSD\|PSP	RPTOR KIAA1303 RAPTOR	NSIAYKATVNARPQRVLDtssLtQsAPAsPtNKGVHIHQAG
Q8N122	S859	EPSD\|PSP	RPTOR KIAA1303 RAPTOR	YKATVNARPQRVLDtssLtQsAPAsPtNKGVHIHQAGGsPP
Q8N122	S863	PSP	RPTOR KIAA1303 RAPTOR	VNARPQRVLDtssLtQsAPAsPtNKGVHIHQAGGsPPAsst
Q8N122	S877	PSP	RPTOR KIAA1303 RAPTOR	tQsAPAsPtNKGVHIHQAGGsPPAsstssssLtNDVAKQPV
Q8NEB9	S249	PSP	PIK3C3 VPS34	KEyGIVYYEKDGDEssPILTsFELVKVPDPQMSMENLVESK
Q8NFG4	S406	PSP	FLCN BHD	SAFEVLRTMLPVGCVRIIPYsSQYEEAYRCNFLGLSPHVQI
Q8NFG4	S537	PSP	FLCN BHD	VLFKFTKVDSRPKEDTQKLLsILGAsEEDNVKLLKFWMTGL
Q8NFG4	S542	PSP	FLCN BHD	TKVDSRPKEDTQKLLsILGAsEEDNVKLLKFWMTGLSKTYK
Q8TDY2	S1323	PSP	RB1CC1 KIAA0203 RBICC	LEQLEEQEKRKNEEMQNVRTsLIAEQQTNFNTVLTREKMRK
Q8TDY2	S943	PSP	RB1CC1 KIAA0203 RBICC	VICLQNEKDQKLLEMENIMHsQNCEIKELKQSREIVLEDLK
Q8TDY2	S986	PSP	RB1CC1 KIAA0203 RBICC	HVENDEKLQLLRAELQsLEQsHLKELEDTLQVRHIQEFEKV
Q8TEV9	S400	EPSD\|PSP	SMCR8	DRMVEKQESIPSKPsQDRPPsssLEECPIPKVLIsVGsYKS
Q8TEV9	S492	EPSD\|PSP	SMCR8	IEVLGTEKSTSVLsKsDsQAsLtVPLsPQVVRSKAVSHRtI
Q8TEV9	S562	EPSD\|PSP	SMCR8	NEEESYPDGNEGAIRFQASIsPPELGETEEGSIENTPSQID
Q8TEV9	T666	EPSD\|PSP	SMCR8	GFPAYELDPSHLLASRDISKtsLDNYSDTTSYVSSVASTSS
Q9BSB4	S11	PSP	ATG101 C12orf44 PP894	__________MNCRSEVLEVsVEGRQVEEAMLAVLHTVLLH
Q9BSB4	S203	PSP	ATG101 C12orf44 PP894	RDVQPYLYKISFQITDALGTsVTTTMRRLIKDTLAL_____
Q9C0C7	S465	PSP	AMBRA1 DCAF3 KIAA1736	VSLLSVLRQQEGGSQASVYTsATEGRGFPASGLATESDGGN
Q9C0C7	S635	PSP	AMBRA1 DCAF3 KIAA1736	QLPPLERTEGQTPsSsRLELsssAsPQEERTVGVAFNQETG
Q9Y4P1	S316	EPSD\|PSP	ATG4B APG4B AUTL1 KIAA0943	DESFHCQHPPCRMSIAELDPsIAVGFFCKTEDDFNDWCQQV
Q9Y6D9	S546	PSP	MAD1L1 MAD1 TXBP181	LERRALQGDYDQSRTKVLHMsLNPTSVARQRLREDHSQLQA